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Browsing by Author Murugesan, Sankaranarayanan

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Issue DateTitleAuthor(s)
2021-09Design, synthesis and evaluation of novel β-carboline ester analogues as potential anti-leishmanial agentsMurugesan, Sankaranarayanan
2022-01Design, synthesis and structure–activity relationship studies of novel spirochromanone hydrochloride analogs as anticancer agentsMurugesan, Sankaranarayanan
2023-01Design, synthesis, anti-acetylcholinesterase evaluation and molecular modelling studies of novel coumarin-chalcone hybridsMurugesan, Sankaranarayanan
2020-07Design, synthesis, in silico studies, and evaluation of novel chalcones and their pyrazoline derivatives for antibacterial and antitubercular activitiesMurugesan, Sankaranarayanan
2020-05Design, synthesis, α-amylase inhibition and in silico docking study of novel quinoline bearing proline derivativesMurugesan, Sankaranarayanan
2020-07Discovery of 1,2,3-triazole based quinoxaline-1,4-di-N-oxide derivatives as potential anti-tubercular agentsMurugesan, Sankaranarayanan
2023-07Discovery of Novel Coumarin-Schiff Base Hybrids as Potential Acetylcholinesterase Inhibitors: Design, Synthesis, Enzyme Inhibition, and Computational StudiesMurugesan, Sankaranarayanan
2023-04Discovery of potent DNMT1 inhibitors against sickle cell disease using structural-based virtual screening, MM-GBSA and molecular dynamics simulation-based approachesMurugesan, Sankaranarayanan
2020-11Druggable targets of SARS-CoV-2 and treatment opportunities for COVID-19Murugesan, Sankaranarayanan
2020-02Formulation and characterization of folate receptor-targeted PEGylated liposome encapsulating bioactive compounds from Kappaphycus alvarezii for cancer therapyMurugesan, Sankaranarayanan
2023-04Further Investigations of Nitroheterocyclic Compounds as Potential Antikinetoplastid Drug CandidatesMurugesan, Sankaranarayanan
2022Graph theoretical network analysis, in silico exploration, and validation of bioactive compounds from Cynodon dactylon as potential neuroprotective agents against α-synucleinMurugesan, Sankaranarayanan
2019Green Synthesis, in-vitro Antimicrobial Evaluation, Docking, and SAR Studies of Potent Quinoline-4-Carboxylic AcidsJha, Prabhat N.; Murugesan, Sankaranarayanan; Shukla, Paritosh
2022-12Identification of Papain-Like Protease inhibitors of SARS CoV-2 through HTVS, Molecular docking, MMGBSA and Molecular dynamics approachMurugesan, Sankaranarayanan
2022-08In silico and in vitro analysis of PPAR – α / γ dual agonists: Comparative evaluation of potential phytochemicals with anti-obesity drug orlistatMurugesan, Sankaranarayanan
2023-07In silico anti-viral assessment of phytoconstituents in a traditional (Siddha Medicine) polyherbal formulation – Targeting Mpro and pan-coronavirus post-fusion Spike proteinMurugesan, Sankaranarayanan
2023-11In Silico Exploration of Bisphosphonate Scaffolds as Potential Inhibitors of SARS-CoV-2 RdRp for COVID-19 and PASCMurugesan, Sankaranarayanan
2020-10In-vivo and in-silico toxicity studies of daidzein: an isoflavone from soyMurugesan, Sankaranarayanan
2020Leishmaniasis is the most widespread pathogenic disease in several countries. Currently, no effective vaccines are available, and the control of Leishmaniasis primarily relies on decade-old chemotherapy. The treatment for the Leishmaniasis is not up to the mark. Current therapy for Leishmaniasis is ancient and requires hospitalization for the administration. These medications are also highly toxic and resistant. β-carboline, a natural indole containing alkaloid, holds a vital position in the field of medicinal chemistry with a diversified pharmacological action. The current review focuses mainly on the anti-leishmanial effects of β-carboline analogs and their synthetic strategies, structural activity relationship studies (SAR). The past ten years alterations unveiled by β-carboline analogs present in phytoconstituents and various derivatives of synthesized analogs with the mechanism of action were briefly shortlisted and illustratedMurugesan, Sankaranarayanan
2022-06Liposomes: An emerging carrier for targeting Alzheimer's and Parkinson's diseasesMurugesan, Sankaranarayanan