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Title: | Neuropharmacological evaluation of a novel 5-HT3 receptor antagonist (6g) on chronic unpredictable mild stress-induced changes in behavioural and brain oxidative stress parameters in mice |
Authors: | Mahesh, R. |
Keywords: | Pharmacy 5-HT3 receptor antagonist Chronic unpredictable mild stress (CUMS) Depression Oxidative stress |
Issue Date: | Mar-2014 |
Publisher: | Wolters Kluwer |
Abstract: | The aim of the study was to evaluate a novel 5 HT3 receptor antagonist (6g) on chronic stress induced changes in behavioural and brain oxidative stress parameter in mice. A complicated relationship exists among stressful stimuli, body's reaction to stress and the onset of clinical depression. Chronic unpredictable stressors can produce a situation similar to human depression, and such animal models can be used for the preclinical evaluation of antidepressants. |
URI: | https://www.ijp-online.com/article.asp?issn=0253-7613;year=2014;volume=46;issue=2;spage=191;epage=196;aulast=Bhatt http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/13165 |
Appears in Collections: | Department of Pharmacy |
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