Etazolate, a phosphodiesterase-4 enzyme inhibitor produces antidepressant-like effects by blocking the behavioral, biochemical, neurobiological deficits and histological abnormalities in hippocampus region caused by olfactory bulbectomy

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DC Field	Value	Language
dc.contributor.author	Mahesh, R.	-
dc.date.accessioned	2023-11-20T04:03:44Z	-
dc.date.available	2023-11-20T04:03:44Z	-
dc.date.issued	2014-08	-
dc.identifier.uri	https://link.springer.com/article/10.1007/s00213-014-3705-0	-
dc.identifier.uri	http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/13168	-
dc.description.abstract	Olfactory bulbectomy (OBX) is a widely used model for antidepressant screening and known to induce neurodegeneration in several brain areas. Our earlier studies demonstrated that etazolate produced antidepressant-like effects in behavioral despair models of depression; however, the potential role of etazolate on behavior and morphological changes in the hippocampus region along with its underlying mechanism(s) following OBX has not been adequately addressed.	en_US
dc.language.iso	en	en_US
dc.publisher	Springer	en_US
dc.subject	Olfactory bulbectomy (OBX)	en_US
dc.subject	Phosphodiesterase-4	en_US
dc.subject	Etazolate	en_US
dc.title	Etazolate, a phosphodiesterase-4 enzyme inhibitor produces antidepressant-like effects by blocking the behavioral, biochemical, neurobiological deficits and histological abnormalities in hippocampus region caused by olfactory bulbectomy	en_US
dc.type	Article	en_US
Appears in Collections:	Department of Pharmacy

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