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DC Field | Value | Language |
---|---|---|
dc.contributor.author | Mahesh, R. | - |
dc.date.accessioned | 2023-11-21T04:47:01Z | - |
dc.date.available | 2023-11-21T04:47:01Z | - |
dc.date.issued | 2014-11 | - |
dc.identifier.uri | https://www.sciencedirect.com/science/article/abs/pii/S0014299914006384 | - |
dc.identifier.uri | http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/13196 | - |
dc.description.abstract | Anxiety disorders are widely spread psychiatric illnesses that are a cause of major concern. Despite a consistent increase in anxiolytics, the prevalence of anxiety is static; this necessitates the development of new compounds with potential activity and minimum unwanted effects. A serotonergic (5HT) system plays an important role in pathogenesis of anxiety and predominantly involves 5HT1A receptor action in mediating anxiety-like behavior; the antagonism of 5HT1A receptor has demonstrated to produce anxiolytic-like effects. Alverine citrate (AVC) is reported as a 5HT1A antagonist; however, its effects on anxiety-like behavior are not investigated. Thus, the present study, by utilizing a neurobehavioral approach, examined the anxiolytic-like effects of AVC in experimental mouse models of anxiety. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Elsevier | en_US |
dc.subject | Pharmacy | en_US |
dc.subject | Anxiety disorders | en_US |
dc.subject | Elevated plus maze (EPM) | en_US |
dc.title | Anxiolytic-like effects of alverine citrate in experimental mouse models of anxiety | en_US |
dc.type | Article | en_US |
Appears in Collections: | Department of Pharmacy |
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