Neuropharmacological and neurochemical evaluation of N-n-propyl-3-ethoxyquinoxaline-2-carboxamide (6n): a novel serotonergic 5-HT3 receptor antagonist for co-morbid antidepressant- and anxiolytic-like potential using traumatic brain injury model in rats

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DC Field	Value	Language
dc.contributor.author	Mahesh, R.	-
dc.date.accessioned	2023-11-23T05:47:12Z	-
dc.date.available	2023-11-23T05:47:12Z	-
dc.date.issued	2016	-
dc.identifier.uri	https://www.degruyter.com/document/doi/10.1515/jbcpp-2016-0057/html	-
dc.identifier.uri	http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/13226	-
dc.description.abstract	Several preclinical studies have shown that serotonergic 5-HT3 receptor antagonists play an important role in the management of neuropsychiatric disorders, such as depression and anxiety. In the present study the compound “6n” (N-n-propyl-3-ethoxyquinoxaline-2-carboxamide), a novel 5-HT3 receptor antagonist with an optimal log P (2.52) and pA2 (7.6) value was screened for its neuro-pharmacological potential in chronic rodent models of depression and anxiety named traumatic brain injury (TBI).	en_US
dc.language.iso	en	en_US
dc.publisher	De Gruyter	en_US
dc.subject	Pharmacy	en_US
dc.subject	Neuropharmacological	en_US
dc.subject	Neurochemical	en_US
dc.subject	Traumatic brain injury (TBI)	en_US
dc.title	Neuropharmacological and neurochemical evaluation of N-n-propyl-3-ethoxyquinoxaline-2-carboxamide (6n): a novel serotonergic 5-HT3 receptor antagonist for co-morbid antidepressant- and anxiolytic-like potential using traumatic brain injury model in rats	en_US
dc.type	Article	en_US
Appears in Collections:	Department of Pharmacy

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