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http://dspace.bits-pilani.ac.in:8080/jspui/xmlui/handle/123456789/13249Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Mahesh, R. | - |
| dc.date.accessioned | 2023-11-24T04:24:49Z | - |
| dc.date.available | 2023-11-24T04:24:49Z | - |
| dc.date.issued | 2016-01 | - |
| dc.identifier.uri | https://www.prd-journal.com/article/S1353-8020(15)00877-9/fulltext | - |
| dc.identifier.uri | http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/13249 | - |
| dc.description.abstract | The prevalence of depression is about 2-3 times higher in diabetic patients compared to the general population, yet this comorbidity is poorly treated. This may partly be contributed to the inefficient pharmacotherapy. We evaluated if a novel 5HT3 receptor antagonist 4i (N-(3-Chloro-2-methylphenyl) quinoxalin-2-carboxamide), can prevent depression-like behavior associated with diabetes in mice. Also, the role of oxidative stress in antidepressant action of 4i was investigated. | en_US |
| dc.language.iso | en | en_US |
| dc.publisher | Elsevier | en_US |
| dc.subject | Pharmacy | en_US |
| dc.subject | Diabetic mice | en_US |
| dc.subject | Antagonists | en_US |
| dc.subject | Antidepressant | en_US |
| dc.title | 4i (N-(3-Chloro-2-methylphenyl) quinoxalin-2-carboxamide), a novel 5-HT3 receptor antagonist alleviates depressive behavior evoked in streptozotocin-induced diabetic mice: Role of oxidative stress | en_US |
| dc.type | Article | en_US |
| Appears in Collections: | Department of Pharmacy | |
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