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dc.contributor.authorJadhav, Hemant R.-
dc.date.accessioned2023-11-24T10:38:31Z-
dc.date.available2023-11-24T10:38:31Z-
dc.date.issued2018-
dc.identifier.urihttps://www.eurekaselect.com/article/83789-
dc.identifier.urihttp://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/13270-
dc.description.abstractHuman Immunodeficiency Virus Type 1 Integrase or HIV-1 integrase (IN) is a 288 amino acid protein that incorporates the retrotranscribed viral DNA into the host chromosomal DNA. Over the past 30 years, large number of derivatives have been evaluated for their inhibitory potential against IN. There is vast literature available which need to be collated to help scientists plan the future drug design. This review discusses the reports of past 25 years on analogs of quinoline, coumarin and other related heterocycles, which exhibit low micromolar inhibitory potency against IN.en_US
dc.language.isoenen_US
dc.publisherBentham Scienceen_US
dc.subjectPharmacyen_US
dc.subjectHIV-1 integraseen_US
dc.subject3'-end processing inhibitorsen_US
dc.subjectHeterocyclic analogsen_US
dc.subjectStrand transfer inhibitorsen_US
dc.titleQuinoline, Coumarin and Other Heterocyclic Analogs Based HIV-1 Integrase Inhibitorsen_US
dc.typeArticleen_US
Appears in Collections:Department of Pharmacy

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