DSpace logo

Please use this identifier to cite or link to this item: http://dspace.bits-pilani.ac.in:8080/jspui/handle/123456789/13295
Title: Small Molecular Inhibitors for the Treatment of Rheumatoid Arthritis: Progress so Far
Authors: Jadhav, Hemant R.
Keywords: Pharmacy
Janus kinase
TNFα-converting enzyme
Tyrosine kinase inhibitors (TKIs)
Peptidyl arginine deiminase
Phosphoinositide 3-kinase
Rheumatoid arthritis
Issue Date: 2015
Publisher: Bentham Science
Abstract: Rheumatoid Arthritis (RA) is an autoimmune disease characterized by persistent inflammation and joint damage. The main aim of RA treatment is to control the disease progress. Despite the success of biologicals like Adalimumab, Atlizumab, infliximab, etc. in treatment of RA, the high cost and associated immunological adverse effects have triggered discovery of small molecules targeting RA. This review describes the last 15 years of small molecular drug discovery in RA, focused mainly on preclinical and clinical studies
URI: https://www.ingentaconnect.com/content/ben/mrmc/2015/00000015/00000002/art00005
http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/13295
Appears in Collections:Department of Pharmacy

Files in This Item:
There are no files associated with this item.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.