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Title: | Graph theoretical network analysis, in silico exploration, and validation of bioactive compounds from Cynodon dactylon as potential neuroprotective agents against α-synuclein |
Authors: | Murugesan, Sankaranarayanan |
Keywords: | Pharmacy In silico ADMET Nolecular dynamics Molecular docking Neuroprotective agents Cynodon dactylon |
Issue Date: | 2022 |
Publisher: | Tabriz University of Medical Sciences |
Abstract: | Parkinson's disease (PD) is a chronic, devastating neurodegenerative disorder marked by the death of dopaminergic neurons in the midbrain's substantia nigra pars compacta (Snpc). In alpha-synuclein (α-Syn) self-aggregation, the existence of intracytoplasmic inclusion bodies called Lewy bodies (LBs) and Lewy neurites (LNs) causes PD, which is a cause of neuronal death. |
URI: | https://bi.tbzmed.ac.ir/Article/bi-24113 http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/13329 |
Appears in Collections: | Department of Pharmacy |
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