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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Taliyan, Rajeev | - |
| dc.date.accessioned | 2023-12-12T10:52:11Z | - |
| dc.date.available | 2023-12-12T10:52:11Z | - |
| dc.date.issued | 2015-08 | - |
| dc.identifier.uri | https://www.degruyter.com/document/doi/10.1515/jbcpp-2015-0021/html | - |
| dc.identifier.uri | http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/13377 | - |
| dc.description.abstract | Hydroxy safflor yellow A (HSYA) has been translated clinically for cardiovascular diseases. HSYA is also greatly acknowledged for its protective effects against cerebral ischemic-reperfusion (I/R) injury. Although the precise mechanism of cerebral I/R injury is not fully understood, oxygen-derived free radicals and mitochondrial permeability transition pore (mPTP) opening during I/R injury are widely recognized as an important contributor to neuronal injury. Thus, we speculated that the neuroprotective effects of HSYA against cerebral I/R injury may be associated with mPTP modulation. | en_US |
| dc.language.iso | en | en_US |
| dc.publisher | De Gruyter | en_US |
| dc.subject | Pharmacy | en_US |
| dc.subject | Carboxyatractyloside | en_US |
| dc.subject | Cerebral ischemic-reperfusion injury | en_US |
| dc.subject | Hydroxy safflor yellow A (HSYA) | en_US |
| dc.subject | Mitochondrial permeability transition pore (mPTP) | en_US |
| dc.title | Neuroprotective effect of hydroxy safflor yellow A against cerebral ischemia-reperfusion injury in rats: putative role of mPTP | en_US |
| dc.type | Article | en_US |
| Appears in Collections: | Department of Pharmacy | |
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