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http://dspace.bits-pilani.ac.in:8080/jspui/handle/123456789/13386| Title: | Protective effect of remote limb post conditioning via upregulation of heme oxygenase-1/BDNF pathway in rat model of cerebral ischemic reperfusion injury |
| Authors: | Taliyan, Rajeev |
| Keywords: | Pharmacy Remote limb ischemic post conditioning (RIPOC) Ischemic reperfusion (I/R) Tumor Necrosis Factor (TNF-α) |
| Issue Date: | Aug-2017 |
| Publisher: | Elsevier |
| Abstract: | Remote ischemic post conditioning (RIPOC) has shown to be neuroprotective against cerebral ischemic reperfusion (I/R) injury. However, the RIPOC protection against I/R injury induced cognitive abnormalities still remains elusive. Abundant evidence from earlier studies highlighted the role of heme oxygenase-1 (HO-1) in neuronal survival in various neurodegenerative disorders. Thus, in the present study, we investigated the possible contribution of HO-1 in RIPOC mediated neuroprotection against cerebral I/R injury and associated cognitive deficits. |
| URI: | https://www.sciencedirect.com/science/article/abs/pii/S0006899317302123 http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/13386 |
| Appears in Collections: | Department of Pharmacy |
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