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http://dspace.bits-pilani.ac.in:8080/jspui/xmlui/handle/123456789/13398| Title: | Effect of pioglitazone on the abrogated cardioprotective effect of ischemic preconditioning in hyperlipidemic rat heart |
| Authors: | Taliyan, Rajeev |
| Keywords: | Pharmacy Creatinine kinase Glycogen synthase kinase-3β Ischemia-reperfusion Lactate dehydrogenase Myocardial injury Pioglitazone Rapamycin Wortmannin |
| Issue Date: | 2016 |
| Publisher: | Medknow |
| Abstract: | The signaling pathways upstream of glycogen synthase kinase-3β (GSK-3β) get reduced during ischemic preconditioning (IPC) in hyperlipidemic rat heart. Pioglitazone, an insulin sensitizer, exerts cardioprotection through GSK-3β. The objective of the study is to investigate the role of pioglitazone on the attenuated cardioprotective effect of IPC in hyperlipidemic rat heart. |
| URI: | https://www.ijp-online.com/article.asp?issn=0253-7613;year=2016;volume=48;issue=1;spage=59;epage=63;aulast=Mittal http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/13398 |
| Appears in Collections: | Department of Pharmacy |
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