Pre-Clinical Investigation of Repaglinide Nanoparticles in High Fat Diet with streptozotocin induced memory impaired rats

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Title:	Pre-Clinical Investigation of Repaglinide Nanoparticles in High Fat Diet with streptozotocin induced memory impaired rats
Authors:	Taliyan, Rajeev
Keywords:	Pharmacy Streptozotocin Repaglinide (REP)
Issue Date:	Jun-2023
Publisher:	Wiley
Abstract:	Diabetes Mellitus is a metabolic disorder characterized by insulin resistance with several metabolic abnormalities which trigger neuronal complications, neurodegeneration, and cognitive impairments. Repaglinide (REP) is an insulinotropic, neuroprotective agent with short-action and poor absorption characteristics. Hence, the present study was aimed to investigate the efficacy of REP-loaded lipid polymer-hybrid nanoparticles (REP-LPHNPs) in High Fat Diet low dose of Streptozotocin (HFD-STZ) induced cognitive deficits wistar rats model.
URI:	https://alz-journals.onlinelibrary.wiley.com/doi/abs/10.1002/alz.065550 http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/13425
Appears in Collections:	Department of Pharmacy

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