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http://dspace.bits-pilani.ac.in:8080/jspui/xmlui/handle/123456789/13431| Title: | Development and Validation of PEG-PCL Based Nanoformulation of Rosiglitazone and Evaluation of its Brain Selectivity in Mice Model of Alzheimer’s disease |
| Authors: | Taliyan, Rajeev |
| Keywords: | Pharmacy Alzheimer’s disease Rosiglitazone |
| Issue Date: | Dec-2021 |
| Publisher: | Alzheimer's Association |
| Abstract: | Type-2 Diabetes Mellitus and insulin resistance increases the risk of Alzheimer’s disease (AD). Recent studies highlighted the role of peroxisome proliferator-activated receptor-gamma (PPAR-γ) in modulation of AD. This study was designed to investigate the effect of rosiglitazone alone or in its nanoformulated form for an effective drug delivery in mice model of AD. |
| URI: | https://alz-journals.onlinelibrary.wiley.com/doi/abs/10.1002/alz.058674 http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/13431 |
| Appears in Collections: | Department of Pharmacy |
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