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Please use this identifier to cite or link to this item: http://dspace.bits-pilani.ac.in:8080/jspui/xmlui/handle/123456789/13439
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dc.contributor.authorGaikwad, Anil Bhanudas-
dc.date.accessioned2023-12-18T11:59:10Z-
dc.date.available2023-12-18T11:59:10Z-
dc.date.issued2009-01-
dc.identifier.urihttps://bpspubs.onlinelibrary.wiley.com/doi/full/10.1038/sj.bjp.0707666-
dc.identifier.urihttp://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/13439-
dc.description.abstractCurcumin has been used to treat cancer, diabetes and other pathologies. However, little is known regarding its role in altering post-translational modifications of histone H3. A recent report suggests that acute hyperglycaemia induces a global down-regulation of gene expression in human tissues and epigenetic regulation of gene expression could be a novel mechanism underlying the pathological processes of hyperglycaemia. The present study was undertaken to examine changes in histone modification by curcumin treatment which prevents development of type I diabetic nephropathy.en_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.subjectPharmacyen_US
dc.subjectDiabetic nephropathyen_US
dc.subjectStreptozotocinen_US
dc.subjectCanceren_US
dc.titleChange in post-translational modifications of histone H3, heat-shock protein-27 and MAP kinase p38 expression by curcumin in streptozotocin-induced type I diabetic nephropathyen_US
dc.typeArticleen_US
Appears in Collections:Department of Pharmacy

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