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DC Field | Value | Language |
---|---|---|
dc.contributor.author | Gaikwad, Anil Bhanudas | - |
dc.date.accessioned | 2023-12-18T11:59:10Z | - |
dc.date.available | 2023-12-18T11:59:10Z | - |
dc.date.issued | 2009-01 | - |
dc.identifier.uri | https://bpspubs.onlinelibrary.wiley.com/doi/full/10.1038/sj.bjp.0707666 | - |
dc.identifier.uri | http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/13439 | - |
dc.description.abstract | Curcumin has been used to treat cancer, diabetes and other pathologies. However, little is known regarding its role in altering post-translational modifications of histone H3. A recent report suggests that acute hyperglycaemia induces a global down-regulation of gene expression in human tissues and epigenetic regulation of gene expression could be a novel mechanism underlying the pathological processes of hyperglycaemia. The present study was undertaken to examine changes in histone modification by curcumin treatment which prevents development of type I diabetic nephropathy. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Wiley | en_US |
dc.subject | Pharmacy | en_US |
dc.subject | Diabetic nephropathy | en_US |
dc.subject | Streptozotocin | en_US |
dc.subject | Cancer | en_US |
dc.title | Change in post-translational modifications of histone H3, heat-shock protein-27 and MAP kinase p38 expression by curcumin in streptozotocin-induced type I diabetic nephropathy | en_US |
dc.type | Article | en_US |
Appears in Collections: | Department of Pharmacy |
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