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Title: | Telmisartan and esculetin combination ameliorates type 2 diabetic cardiomyopathy by reversal of H3, H2A, and H2B histone modifications |
Authors: | Gaikwad, Anil Bhanudas |
Keywords: | Pharmacy Telmisartan H2B histone Type 2 diabetic (T2D) |
Issue Date: | Sep-2017 |
Publisher: | PMC |
Abstract: | Although cardioprotective effects of telmisartan are well explored, its effects on epigenetic alterations associated with type 2 diabetic (T2D) cardiomyopathy remain unmapped. Thus, the present study was designed to evaluate the potential of esculetin and telmisartan combination to reverse histone posttranslational modifications (PTMs) in curbing T2D cardiomyopathy. |
URI: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830845/ http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/13486 |
Appears in Collections: | Department of Pharmacy |
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