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http://dspace.bits-pilani.ac.in:8080/jspui/xmlui/handle/123456789/13539| Title: | Apoptosis inducing activity of steroidal constituents from Solanum xanthocarpum and Asparagus racemosus |
| Authors: | Paul, Atish Tulshiram |
| Keywords: | Pharmacy Anticancer activity Apoptosis Sarsapogenin and Diosgenin derived steroidal constituents Glycoalkaloids Solanum xanthocarpum Asparagus racemosus |
| Issue Date: | Aug-2010 |
| Publisher: | Elsevier |
| Abstract: | A series of Sarsapogenin and Diosgenin derived steroidal constituents (1-12), isolated from Solanum xanthocarpum and Asparagus racemosus were screened for their ability to induce cell death and apoptosis of colon carcinoma cells. The carbohydrate moieties linked to the steroid backbones were found to strongly influence cytotoxic activity and cell death mode (apoptosis or necrosis). Compound 10, from A. racemosus was found to be a potent inducer of apoptosis. |
| URI: | https://www.sciencedirect.com/science/article/pii/S0944711310000334 http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/13539 |
| Appears in Collections: | Department of Pharmacy |
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