Please use this identifier to cite or link to this item:
http://dspace.bits-pilani.ac.in:8080/jspui/xmlui/handle/123456789/13674
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Mittal, Anupama | - |
dc.contributor.author | Chitkara, Deepak | - |
dc.date.accessioned | 2024-01-05T06:40:55Z | - |
dc.date.available | 2024-01-05T06:40:55Z | - |
dc.date.issued | 2016-01 | - |
dc.identifier.uri | https://www.future-science.com/doi/abs/10.4155/tde.15.90 | - |
dc.identifier.uri | http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/13674 | - |
dc.description.abstract | Polymeric micelles are macromolecular nanoconstructs which are formed by self-assembly of synthetic amphiphilic block copolymers. These copolymers could be chemically modified to expand their functionality and hence obtain a multifunctional micelle which could serve several functions simultaneously, for example, long circulation time along with active targeting, smart polymeric micelles providing on-demand drug release for example, pH responsive micelles, redox- and light-sensitive micelles, charge-conversion micelles and core/shell cross-linked micelles. Additionally, micelles could be tailored to carry a contrast agent or siRNA/miRNA along with the drug for greater clinical benefit. The focus of the current commentary would be to highlight such chemical modifications which impart multifunctionality to a single carrier and discuss challenges involved in clinical translation of these multifunctional micelles. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Future Science Group | en_US |
dc.subject | Pharmacy | en_US |
dc.subject | Cross-linked | en_US |
dc.subject | Stimuli-responsive | en_US |
dc.subject | Site-specific | en_US |
dc.subject | Polymeric micelles | en_US |
dc.title | Structural modifications in polymeric micelles to impart multifunctionality for improved drug delivery | en_US |
dc.type | Article | en_US |
Appears in Collections: | Department of Pharmacy |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.