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http://dspace.bits-pilani.ac.in:8080/jspui/xmlui/handle/123456789/13692| Title: | Human umbilical cord blood-mesenchymal stem cell derived exosomes as an efficient nanocarrier for Docetaxel and miR-125a: Formulation optimization and anti-metastatic behaviour |
| Authors: | Chitkara, Deepak Mittal, Anupama |
| Keywords: | Pharmacy MSC Exosomes Docetaxel Metastasis Multi-nucleation |
| Issue Date: | Jun-2023 |
| Publisher: | Elsevier |
| Abstract: | Exosomes, as a nanocarrier for the co-delivery of biologicals and small anticancer molecules is yet in its infancy. Herein, we investigated hUCBMSC derived exosomes as a biogenic nanocarrier for the co-delivery of tumor suppressor miR-125a and microtubule destabilizing Docetaxel (DTX) to target the proliferative and migratory aggressiveness of the murine TNBC 4T1 cells. |
| URI: | https://www.sciencedirect.com/science/article/pii/S0024320523002552 http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/13692 |
| Appears in Collections: | Department of Pharmacy |
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