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Please use this identifier to cite or link to this item: http://dspace.bits-pilani.ac.in:8080/jspui/handle/123456789/13751
Title: CD44 receptor-targeted novel drug delivery strategies for rheumatoid arthritis therapy
Authors: Singhvi, Gautam
Keywords: Pharmacy
CD44
Athritis therapy
Rheumatoid arthritis (RA)
Issue Date: Jul-2021
Publisher: Taylor & Francis
Abstract: Rheumatoid arthritis (RA) is a chronic systemic inflammatory condition that mainly affects the lining of the synovial joints. It can progressively cause disability and even premature death. Moreover, it is associated with substantial socioeconomic burdens [Citation1]. Currently, RA affects more than 23 million people globally, including 12.6 million Indians [Citation1]. Recent findings have suggested the involvement of genetic factors in the development of RA. The HLA-DRB1 alleles that code shared epitopes (conserved sequence of amino acids in positions 70–74 of HLA-DRβ chains) are associated with the structural severity of RA. It was reported that more than 80% of the RA-affected individuals carry the HLA-DRB1*04 cluster, in which *04 signifies the allele group which corresponds to the serological type [Citation1]
URI: https://www.tandfonline.com/doi/full/10.1080/17425247.2021.1950686
http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/13751
Appears in Collections:Department of Pharmacy

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