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http://dspace.bits-pilani.ac.in:8080/jspui/xmlui/handle/123456789/13807| Title: | Disulfiram potentiates docetaxel cytotoxicity in breast cancer cells through enhanced ROS and autophagy |
| Authors: | Chowdhury, Rajdeep Roy, Aniruddha |
| Keywords: | Pharmacy Disulfiram Breast cancer Autophagy |
| Issue Date: | Jul-2020 |
| Publisher: | Springer |
| Abstract: | Recent studies have demonstrated that autophagy plays a critical role in reducing the drug sensitivity of docetaxel (DTX) therapy. Disulfiram (DSF) has exhibited potent autophagy inducing activity in multiple studies. We hypothesized that DSF co-treatment could sensitize breast cancer cells to DTX therapy via autophagy modulation. |
| URI: | https://link.springer.com/article/10.1007/s43440-020-00122-1 http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/13807 |
| Appears in Collections: | Department of Pharmacy |
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