Metformin and glitazones: does similarity in biomolecular mechanism originate from tautomerism in these drugs?

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DC Field	Value	Language
dc.contributor.author	Sundriyal, Sandeep	-
dc.date.accessioned	2024-01-17T09:02:59Z	-
dc.date.available	2024-01-17T09:02:59Z	-
dc.date.issued	2007-11	-
dc.identifier.uri	https://onlinelibrary.wiley.com/doi/abs/10.1002/poc.1273	-
dc.identifier.uri	http://dspace.bits-pilani.ac.in:8080/jspui/xmlui/handle/123456789/13862	-
dc.description.abstract	This theoretical study attempts to find out similarity between metformin and glitazone class of antidiabetic drugs. It was found that some tautomeric forms of both metformin and thiazolidinedione ring of glitazones have similar molecular electrostatic potential (MESP) surface and may bind to a common complementary surface. Complexation and docking studies were also carried out in order to support this hypothesis.	en_US
dc.language.iso	en	en_US
dc.publisher	Wiley	en_US
dc.subject	Pharmacy	en_US
dc.subject	Biomolecular mechanism	en_US
dc.subject	Metformin	en_US
dc.subject	Glitazones	en_US
dc.title	Metformin and glitazones: does similarity in biomolecular mechanism originate from tautomerism in these drugs?	en_US
dc.type	Article	en_US
Appears in Collections:	Department of Pharmacy

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