AzaGly-Appended Peptidomimetics Structurally Related to PTR6154 as Potential PKB/Akt Inhibitors

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DC Field	Value	Language
dc.contributor.author	Shrivastava, Richa	-
dc.date.accessioned	2024-01-19T10:22:18Z	-
dc.date.available	2024-01-19T10:22:18Z	-
dc.date.issued	2017-04	-
dc.identifier.uri	https://chemistry-europe.onlinelibrary.wiley.com/doi/abs/10.1002/cbic.201700031	-
dc.identifier.uri	http://dspace.bits-pilani.ac.in:8080/jspui/xmlui/handle/123456789/13891	-
dc.description.abstract	Synthesis of AzaGly-appended peptidomimetics with improved biological and biochemical properties. Robust synthesis of azapeptide on solid support is demonstrated without noticeable hydantoin formation. The azapeptide derived from the GSK-3β substrate exhibited improved properties in terms of Akt kinase inhibitory activity and basal degradation, proteolytic degradation, conformation and binding affinities.	en_US
dc.language.iso	en	en_US
dc.publisher	Wiley	en_US
dc.subject	Pharmacy	en_US
dc.subject	Peptidomimetics	en_US
dc.subject	PKB/Akt Inhibitors	en_US
dc.title	AzaGly-Appended Peptidomimetics Structurally Related to PTR6154 as Potential PKB/Akt Inhibitors	en_US
dc.type	Article	en_US
Appears in Collections:	Department of Pharmacy

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