Force induced unzipping of dsDNA: The solvent effect

Singh, Navin

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DC Field	Value	Language
dc.contributor.author	Singh, Navin	-
dc.date.accessioned	2024-02-20T04:49:45Z	-
dc.date.available	2024-02-20T04:49:45Z	-
dc.date.issued	2013	-
dc.identifier.uri	http://www.cognizure.com/abstract.aspx?p=106637288	-
dc.identifier.uri	http://dspace.bits-pilani.ac.in:8080/jspui/xmlui/handle/123456789/14359	-
dc.description.abstract	The salt concentration of the solution plays an important role in the stabilization of double stranded DNA (dsDNA) molecule. In our work, the Hamiltonian in Peyrard-Bishop Dauxois (PBD) model of a heterogeneous chain has been modified with a stabilizing solvent interaction term. This term strengthens the base pair dissociation energy and stabilizes the hydrogen bonds between complementary strands of dsDNA. To study the effect of salt concentration we have modified the potentials appearing in this model. We investigated the influence of salt concentration on the force required to unzip the chain. The force induced unzipping is studied in both constant extension ensemble (CEE) and constant force ensemble (CFE). We found that the results are independent of choice of the ensembles and are in good agreement with the experimental results	en_US
dc.language.iso	en	en_US
dc.publisher	Physics Express	en_US
dc.subject	Physics	en_US
dc.subject	Double stranded DNA (ds-DNA)	en_US
dc.subject	DNA unzipping	en_US
dc.subject	Peyrard-Bishop Dauxois model	en_US
dc.subject	Constant extension ensemble	en_US
dc.subject	Constant force ensemble	en_US
dc.title	Force induced unzipping of dsDNA: The solvent effect	en_US
dc.type	Article	en_US
Appears in Collections:	Department of Physics

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