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Title: | Camel Milk α-lactalbumin As A Potential Anticancer Molecule: A Bioinformatics Analysis |
Authors: | Dubey, Uma S. |
Keywords: | Biology Camel milk Anti-cancer HAMLET Computational analysis DNA Physicochemical properties Amini acid |
Issue Date: | 2020 |
Publisher: | Research Journal of Pharmaceutical, Biological and Chemical Sciences |
Abstract: | α-lactalbumin-Oleic acid complex derived from milk is well known to have anti-cancer properties in many diverse mammalian species including humans, goats and cows. The objective of the current study is to see if α-lactalbumin present in camel’s milk too can serve as a potential anti-cancer molecule in its complex form. A comparative evaluation of α-lactalbumin structure among four mammalian species, viz, Camelusferus, Bostaurus, Homo sapiens, and Capra hircus has been made between the nucleotide sequences and structures of protein. Furthermore, the physico-chemical properties, amino acid composition, position of disulfide bridge formation in these species has been compared. The outcome of the present study suggests the presence of an anti-cancer property in the α-lactalbumin of camel, as has been experimentally observed in the other three species. |
URI: | https://www.rjpbcs.com/pdf/2020_11(3)/%5B5%5D.pdf http://dspace.bits-pilani.ac.in:8080/jspui/xmlui/handle/123456789/15357 |
Appears in Collections: | Department of Biological Sciences |
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