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http://dspace.bits-pilani.ac.in:8080/jspui/handle/123456789/15359| Title: | Regulation of shelterin proteins TERF2IP and TRF2 by H3K4me3-p65 axis drives hyperglycemia dependent endothelial senescence |
| Authors: | Majumder, Syamantak Chowdhury, Shibasish |
| Keywords: | Biology TERF2IP |
| Issue Date: | May-2023 |
| Abstract: | Endothelial senescence has been linked to several cardiovascular diseases. Dysregulation of proteins of the shelterin complex including TRF2 and TERF2IP causes senescence as it hampers DNA repair and cell proliferation. However, whether exposure to hyperglycemia interplays with proteins of the shelterin complex thus further dictates the senescent phenotype of endothelial cells (EC) remain to be explored. |
| URI: | URL https://www.biorxiv.org/content/10.1101/2023.05.12.540614v2 http://dspace.bits-pilani.ac.in:8080/jspui/xmlui/handle/123456789/15359 |
| Appears in Collections: | Department of Biological Sciences |
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