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http://dspace.bits-pilani.ac.in:8080/jspui/handle/123456789/15511| Title: | Cobalt-catalyzed tandem one-pot synthesis of polysubstituted imidazo[1,5-a]pyridines and imidazo[1,5-a]isoquinolines |
| Authors: | Kumar, Anil |
| Keywords: | Chemistry Cobalt-catalyzed |
| Issue Date: | 2022 |
| Publisher: | RSC |
| Abstract: | An efficient cobalt-catalyzed tandem one-pot method has been developed for the synthesis of polysubstituted imidazo[1,5-a]-N-heteroaromatics. The method involves Knoevenagel condensation followed by cobalt-catalyzed direct alkenylation to give the desired polysubstituted imidazo[1,5-a]pyridines and imidazo[1,5-a]isoquinolines in a one-pot manner. This method exhibits a broad substrate scope, provides moderate to good (39–74%) yields and is amenable to scale-up to the gram scale. An efficient cobalt-catalyzed tandem one-pot method has been developed for the synthesis of polysubstituted imidazo[1,5-a]-N-heteroaromatics. |
| URI: | https://www.sciencedirect.com/org/science/article/abs/pii/S1477052022095957#! http://dspace.bits-pilani.ac.in:8080/jspui/xmlui/handle/123456789/15511 |
| Appears in Collections: | Department of Chemistry |
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