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Title: | Computational and in vitro Investigation of miRNA-Gene Regulations in Retinoblastoma Pathogenesis: miRNA Mimics Strategy |
Authors: | Deepa, P.R. |
Keywords: | Biology bio-informatics analysis miRNA-mRNA Mimics Retinoblastoma |
Issue Date: | 2015 |
Publisher: | Sage |
Abstract: | Retinoblastoma (RB), a primary pediatric intraocular tumor, arises from primitive retinal layers. Several novel molecular strategies are being developed for the clinical management of RB. miRNAs are known to regulate cancer-relevant biological processes. Here, the role of selected miRNAs, namely, miR-532-5p and miR-486-3p, has been analyzed for potential therapeutic targeting in RB. |
URI: | https://journals.sagepub.com/doi/10.4137/BBI.S21742 http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/2102 |
Appears in Collections: | Department of Biological Sciences |
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