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DC Field | Value | Language |
---|---|---|
dc.contributor.author | Deepa, P.R. | - |
dc.date.accessioned | 2021-09-19T16:02:05Z | - |
dc.date.available | 2021-09-19T16:02:05Z | - |
dc.date.issued | 2009 | - |
dc.identifier.uri | https://www.tandfonline.com/doi/abs/10.3109/02713680903291139 | - |
dc.identifier.uri | http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/2120 | - |
dc.description.abstract | Retinoblastoma (RB) is the most common primary intraocular malignancy of infancy and childhood, where tumor invasion into the choroid, optic nerve, and/or orbit are risk factors for metastasis. Here we have correlated oxidative stress with the clinicopathologic characteristics of retinoblastoma. Methods: Tumor samples were processed for histopathologic examination. Malondialdehyde, a biomarker of oxidative stress, was immunohistochemically analyzed in 34 archival retinoblastoma tumor specimens, which included 17 tumors that did not have any invasion of the choroid, optic nerve, and/or orbit, and another 17 tumors that had some form of invasion of the choroid, optic nerve, and/or orbit. Lipid peroxidation levels were biochemically measured in another cohort of retinoblastoma tissue samples (nā=ā16), and correlated clinicopathologically. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Taylor & Francis | en_US |
dc.subject | Biology | en_US |
dc.subject | Oxidative Stress | en_US |
dc.subject | Retinoblastoma | en_US |
dc.subject | Tumor Invasiveness | en_US |
dc.title | Oxidative Stress in Retinoblastoma: Correlations with Clinicopathologic Features and Tumor Invasiveness | en_US |
dc.type | Article | en_US |
Appears in Collections: | Department of Biological Sciences |
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