Verteporfin disrupts multiple steps of autophagy and regulates p53 to sensitize osteosarcoma cells

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DC Field	Value	Language
dc.contributor.advisor
dc.contributor.advisor
dc.contributor.author	Chowdhury, Rajdeep
dc.contributor.author	Chowdhury, Shibasish
dc.contributor.author
dc.contributor.author	Mukherjee, Sudeshna
dc.date.accessioned	2021-09-27T07:47:10Z
dc.date.available	2021-09-27T07:47:10Z
dc.date.issued	2021-01
dc.identifier.uri	https://cancerci.biomedcentral.com/articles/10.1186/s12935-020-01720-y
dc.identifier.uri	http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/2141
dc.description.abstract	Osteosarcoma (OS) is a malignant tumor of the bone mostly observed in children and adolescents. The current treatment approach includes neoadjuvant and adjuvant chemotherapy; however, drug resistance often hinders therapy in OS patients. Also, the post-relapse survival of OS patients is as low as 20%. We therefore planned to understand the molecular cause for its poor prognosis and design an appropriate therapeutic strategy to combat the disease.	en_US
dc.language.iso	en	en_US
dc.publisher	Springer Nature	en_US
dc.subject	Biology	en_US
dc.subject	Verteporfin	en_US
dc.subject	Autophagy	en_US
dc.subject	Osteosarcoma cells	en_US
dc.title	Verteporfin disrupts multiple steps of autophagy and regulates p53 to sensitize osteosarcoma cells	en_US
dc.type	Article	en_US
Appears in Collections:	Department of Biological Sciences

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