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Please use this identifier to cite or link to this item: http://dspace.bits-pilani.ac.in:8080/jspui/handle/123456789/2426
Title: G-Protein–Coupled Receptor Kinase Interacting Protein-1 Mediates Intima Formation by Regulating Vascular Smooth Muscle Proliferation, Apoptosis, and Migration
Authors: Majumder, Syamantak
Keywords: Biology
G-protein–coupled receptor kinase
Migration
Apoptosis
Issue Date: 21-Feb-2013
Publisher: AHA Journals
Abstract: The G-protein–coupled receptor kinase interacting protein-1 (GIT1) is a scaffold protein that is important for phospholipase Cγ and extracellular signal-regulated kinase 1/2 signaling induced by angiotensin II and epidermal growth factor. Because GIT1 regulates signaling by several vascular smooth muscle cell (VSMC) growth factors, we hypothesized that intima formation would be inhibited by GIT1 depletion.
URI: https://www.ahajournals.org/doi/10.1161/ATVBAHA.112.300966
http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/2426
Appears in Collections:Department of Biological Sciences

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