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Title: | The synthesis of amino acid derived glycoconjugates and the investigation of their anti-inflammatory and analgesic properties |
Authors: | Sah, Ajay Kumar |
Keywords: | Chemistry Synthesis Amino acids Anti-inflammatory Analgesic |
Issue Date: | 2014 |
Abstract: | A series of 4,6-O-ethylidene-β-D-glucopyranosylamine derived glycoconjugates containing amino- and aromatic acids have been synthesized. All these molecules have been tested for their anti-inflammatory and analgesic activity on Wistar rat and Swiss Albino mice respectively. The anti-inflammatory studies were explored using a carrageenan induced paw oedema model while an acetic acid induced writhing model was adapted for the analgesic studies. All of the compounds exhibited anti-inflammatory and analgesic activity in the range of 63–84% and 86–94% respectively. |
URI: | https://pubs.rsc.org/en/content/articlelanding/2014/RA/c3ra43201g http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/2782 |
Appears in Collections: | Department of Chemistry |
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