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DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kumar, Anil | - |
dc.date.accessioned | 2021-10-14T13:10:04Z | - |
dc.date.available | 2021-10-14T13:10:04Z | - |
dc.date.issued | 2020 | - |
dc.identifier.uri | https://pubag.nal.usda.gov/catalog/7074024 | - |
dc.identifier.uri | http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/2814 | - |
dc.description.abstract | A simple and facile method for the synthesis of 3-(arylthio)imidazo[1,2-a]pyridin-2-ols has been developed by a KOH-mediated reaction of 2-aminopyridinium bromides with aryl thiols. The method afforded a wide range of 3-(arylthio)imidazo[1,2-a]pyridin-2-ols in moderate to excellent (56–95%) yields with excellent functional group tolerance. Synthetic utility of the protocol was demonstrated by gram-scale reaction and preparation of 2-aryl-3-(p-tolylthio)imidazo[1,2-a]pyridines from 3-(p-tolylthio)imidazo[1,2-a]pyridin-2-ol. | en_US |
dc.language.iso | en | en_US |
dc.publisher | USDA | en_US |
dc.subject | Chemistry | en_US |
dc.subject | Bromides | en_US |
dc.subject | Methodology | en_US |
dc.subject | Pyridines | en_US |
dc.subject | Thiols | en_US |
dc.subject | Utilities | en_US |
dc.title | KOH-mediated intramolecular amidation and sulfenylation: A direct approach to access 3-(arylthio)imidazo[1,2-a]pyridin-2-ols | en_US |
dc.type | Article | en_US |
Appears in Collections: | Department of Chemistry |
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