Copper and palladium-catalyzed sequential reactions: one-pot synthesis of isoindolo[2,1-b]isoquinolin-7(5H)-ones

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DC Field	Value	Language
dc.contributor.author	Kumar, Anil	-
dc.date.accessioned	2021-10-14T13:10:55Z	-
dc.date.available	2021-10-14T13:10:55Z	-
dc.date.issued	2019	-
dc.identifier.uri	https://pubs.rsc.org/en/content/articlelanding/2019/ob/c9ob00440h	-
dc.identifier.uri	http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/2821	-
dc.description.abstract	A highly efficient protocol has been developed for the synthesis of diversely substituted isoindolo[2,1-b]isoquinolin-7(5H)-ones through sequential Cu(II)-catalyzed Sonogashira coupling, intramolecular hydroamidation followed by palladium-catalyzed ligand-free Heck reaction. Good to excellent yields (41–94%) were observed with excellent substrate scope and functional group tolerance. The developed method represents a practical strategy for the construction of bioactive isoindolo[2,1-b]isoquinolin-7(5H)-ones.	en_US
dc.language.iso	en	en_US
dc.publisher	RSC	en_US
dc.subject	Chemistry	en_US
dc.subject	Copper	en_US
dc.subject	Palladium-catalyzed	en_US
dc.subject	Isoindolo	en_US
dc.title	Copper and palladium-catalyzed sequential reactions: one-pot synthesis of isoindolo[2,1-b]isoquinolin-7(5H)-ones	en_US
dc.type	Article	en_US
Appears in Collections:	Department of Chemistry

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