Sequential Copper-Catalyzed Sonogashira Coupling, Hydroamination and Palladium-Catalyzed Intramolecular Direct Arylation: Synthesis of Azepino-Fused Isoindolinones

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DC Field	Value	Language
dc.contributor.author	Kumar, Anil	-
dc.date.accessioned	2021-10-14T13:11:25Z	-
dc.date.available	2021-10-14T13:11:25Z	-
dc.date.issued	2017-11-09	-
dc.identifier.uri	https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/ejoc.201701379	-
dc.identifier.uri	http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/2829	-
dc.description.abstract	A modular synthesis of azepino-fused isoindolinones has been developed in form of a sequential copper- and palladium-catalyzed tandem reaction. The developed protocol involved the formation of one carbon–nitrogen and two carbon–carbon bonds in a one-pot fashion. The palladium-catalyzed intramolecular direct-arylation step involves the formation of an unusual eight-membered palladacycle.	en_US
dc.language.iso	en	en_US
dc.publisher	Wiley	en_US
dc.subject	Chemistry	en_US
dc.subject	Copper-Catalyzed	en_US
dc.subject	Sonogashira Coupling	en_US
dc.subject	Azepino-Fused Isoindolinones	en_US
dc.title	Sequential Copper-Catalyzed Sonogashira Coupling, Hydroamination and Palladium-Catalyzed Intramolecular Direct Arylation: Synthesis of Azepino-Fused Isoindolinones	en_US
dc.type	Article	en_US
Appears in Collections:	Department of Chemistry

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