A Facile Synthesis of Quinazolin-4(3H)-ones via Copper-Catalyzed One-Pot, Three-Component Tandem Reaction

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DC Field	Value	Language
dc.contributor.author	Kumar, Anil	-
dc.contributor.author	Kumar, Dalip	-
dc.date.accessioned	2021-10-14T13:12:12Z	-
dc.date.available	2021-10-14T13:12:12Z	-
dc.date.issued	2017-09-13	-
dc.identifier.uri	https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/slct.201701778	-
dc.identifier.uri	http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/2832	-
dc.description.abstract	A simple and convenient one-pot, three-component tandem reaction has been developed for the synthesis of substituted quinazolin-4(3H)-ones using CuI/L-proline as catalytic system. A series of 35 quinazolin-4(3H)-ones was synthesized in good to high yield. The method involves copper-catalyzed double C−N coupling, reductive amination, condensation, cyclization and aerobic oxidation. Good functional group tolerance, mild reaction condition, readily available starting materials and user friendly procedure makes this protocol practically good and attractive method for the synthesis of quinazolin-4(3H)-ones.	en_US
dc.language.iso	en	en_US
dc.publisher	Wiley	en_US
dc.subject	Chemistry	en_US
dc.subject	Facile Synthesis	en_US
dc.subject	Copper-Catalyzed	en_US
dc.title	A Facile Synthesis of Quinazolin-4(3H)-ones via Copper-Catalyzed One-Pot, Three-Component Tandem Reaction	en_US
dc.type	Article	en_US
Appears in Collections:	Department of Chemistry

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