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Title: | Synthesis of indole-annulated sulfur heterocycles using copper-catalysed C–N coupling and palladium-catalysed direct arylation |
Authors: | Kumar, Anil |
Keywords: | Chemistry Copper-catalysed |
Issue Date: | 2016 |
Publisher: | RSC |
Abstract: | A simple and efficient method for the synthesis of biologically relevant 5H-benzo[4,5][1,3]thiazino[3,2-a]indoles and 5,7-dihydroisothiochromeno[3,4-b]indoles has been developed via intramolecular copper catalysed Ullmann-type C–N coupling and palladium catalysed direct arylation from the corresponding precursors 2-(2-bromobenzylthio)-1H-indole and 2-(2-bromobenzylthio)-1-methyl-1H-indole, respectively, in good to excellent yields. |
URI: | https://pubs.rsc.org/en/Content/ArticleLanding/OB/2016/C6OB00117C http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/2846 |
Appears in Collections: | Department of Chemistry |
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