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DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kumar, Anil | - |
dc.date.accessioned | 2021-10-14T13:13:29Z | - |
dc.date.available | 2021-10-14T13:13:29Z | - |
dc.date.issued | 2016 | - |
dc.identifier.uri | https://pubs.rsc.org/en/content/articlelanding/2016/ob/c5ob02469b | - |
dc.identifier.uri | http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/2848 | - |
dc.description.abstract | A simple and efficient one-pot protocol has been demonstrated for the synthesis of imidazo[1,2-c]quinazoline derivatives through a copper catalyzed tandem reaction between substituted 2-(2-bromophenyl)-1H-imidazoles and formamide. The synthetic protocol involves initial Ullmann-type C–N coupling followed by intramolecular dehydrative cyclization. The method uses readily available 2-(2-bromophenyl)-1H-imidazoles as the starting materials to afford imidazo[1,2-c]quinazolines in moderate to good yields and provided 610 mg (71%) yield of 3a from a gram scale reaction. | en_US |
dc.language.iso | en | en_US |
dc.publisher | RSC | en_US |
dc.subject | Chemistry | en_US |
dc.subject | Copper-Catalyzed | en_US |
dc.subject | Dehydrative cyclization | en_US |
dc.title | Copper-catalyzed tandem Ullmann type C–N coupling and dehydrative cyclization: synthesis of imidazo[1,2-c]quinazolines | en_US |
dc.type | Article | en_US |
Appears in Collections: | Department of Chemistry |
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