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Title: | Synthesis of 5,7-diarylpyrazolo[1,5-a]pyrimidines via KOH mediated tandem reaction of 1H-pyrazol-3-amines and chalcones |
Authors: | Kumar, Anil |
Keywords: | Chemistry Synthesis |
Issue Date: | 2016 |
Publisher: | INFOFNA |
Abstract: | An efficient and facile protocol has been developed for the synthesis of pyrazolo[1,5-a]pyrimidines through the tandem reaction of 3-aminopyrazoles and chalcones in the presence of catalytic amounts of KOH. The reported method offers access to 5,7-diarylpyrazolo[1,5-a]pyrimidines in good to excellent yields. A gram-scale reaction has been performed to demonstrate the potency of optimized procedure for the scale-up processes |
URI: | https://www.infona.pl/resource/bwmeta1.element.elsevier-c53c9ff9-a1c8-3178-b01b-eb760ed36407 http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/2868 |
Appears in Collections: | Department of Chemistry |
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