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Title: | Ionic liquid phase synthesis (IoLiPS) of 2-aminothiazoles and imidazo[1,2-a]pyridines |
Authors: | Kumar, Anil |
Keywords: | Chemistry IoLiPS Synthesis Aminothiazoles |
Issue Date: | 2014 |
Publisher: | RSC |
Abstract: | An efficient and practical ionic liquid phase synthesis (IoLiPS) of aza-heterocycles has been developed through a ‘catch-and-release’ strategy using an ionic liquid-supported hypervalent iodine reagent. The hypervalent iodine played a dual role as a reagent and as a soluble support. This strategy provided a combinatorial approach for the synthesis of 2-aminothiazoles and imidazo[1,2-a]pyridines directly from substituted acetophenones in good to excellent yields. The use of an ionic liquid supported reagent offered better isolation of the products by simple extraction with organic solvents. |
URI: | https://pubs.rsc.org/en/Content/ArticleLanding/2014/RA/c4ra08009b http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/2874 |
Appears in Collections: | Department of Chemistry |
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