Synthesis of Aza-Fused Isoquinolines through Domino Cross-Aldol Condensation and Palladium-Catalyzed Intramolecular Direct Arylation

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DC Field	Value	Language
dc.contributor.author	Kumar, Anil	-
dc.contributor.author	Kumar, Dalip	-
dc.date.accessioned	2021-10-17T13:57:45Z	-
dc.date.available	2021-10-17T13:57:45Z	-
dc.date.issued	2014	-
dc.identifier.uri	https://agris.fao.org/agris-search/search.do?recordID=US201800063640	-
dc.identifier.uri	http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/2876	-
dc.description.abstract	A straightforward method has been developed for the synthesis of aroyl-substituted imidazo-/benzimidazo-fused isoquinolines. The cascade reaction proceeds via a cross-aldol condensation of 2-(1H-imidazol-1-yl/benzimidazolyl-1-yl)-1-arylethanones and 2-bromobenzaldehyde followed by palladium-catalyzed intramolecular Câ H functionalization. This approach offers a simple and efficient alternative one-pot protocol for the assembly of imidazo/benzimidazo[2,1-a]isoquinolines in moderate to good yields.	en_US
dc.language.iso	en	en_US
dc.publisher	AGRIS	en_US
dc.subject	Chemistry	en_US
dc.subject	Isoquinolines	en_US
dc.subject	Palladium-catalyzed	en_US
dc.title	Synthesis of Aza-Fused Isoquinolines through Domino Cross-Aldol Condensation and Palladium-Catalyzed Intramolecular Direct Arylation	en_US
dc.type	Article	en_US
Appears in Collections:	Department of Chemistry

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