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Title: | Ligand-Free, Copper-Catalyzed Ullmann-Type C–N Coupling: Regioselective Synthesis of Azole-Substituted Imidazo[1,2-a]pyridines |
Authors: | Kumar, Anil |
Keywords: | Chemistry Copper Ligand-free C–N coupling Imidazo[1,2-a]pyridines |
Issue Date: | 2013 |
Publisher: | Thieme |
Abstract: | A simple and highly efficient protocol for the regioselective synthesis of azole-substituted imidazo[1,2-a]pyridines has been developed using a ligand-free, copper-catalyzed Ullmann-type C–N coupling of 2-(2-bromophenyl)imidazo[1,2-a]pyridines with different azoles and in situ generated 1,2,3-triazoles. The reactions proceeded smoothly to furnish azolo-imidazo[1,2-a]pyridines in good to excellent yields (65–96%). |
URI: | https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0033-1339927 http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/2891 |
Appears in Collections: | Department of Chemistry |
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