Please use this identifier to cite or link to this item:
http://dspace.bits-pilani.ac.in:8080/jspui/xmlui/handle/123456789/2895
Title: | Synthesis and Biological Evaluation of 2-Arylamino-5- (3′-Indolyl)-1,3,4-Oxadiazoles as Potent Cytotoxic Agents |
Authors: | Kumar, Anil Kumar, Dalip |
Keywords: | Chemistry Synthesis Biological Evaluation Potent Cytotoxic Agents |
Issue Date: | 2013 |
Publisher: | Wiley |
Abstract: | Coupling of two key scaffolds in medicinal chemistry, the indole and 1,3,4-oxadiazole ring systems, gave rise to 2-arylamino-5-(3′-indolyl)-1,3,4-oxadiazoles with IC50 values in the nanomolar range against a panel of tumor cell lines. Preliminary structure–activity relationship studies indicate potential for improved selectivity through further manipulation of the oxadiazole C-2 and C-5 positions. |
URI: | https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/cmdc.201300221 http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/2895 |
Appears in Collections: | Department of Chemistry |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.