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http://dspace.bits-pilani.ac.in:8080/jspui/xmlui/handle/123456789/2918| Title: | A Facile Synthesis and Cytotoxicity of a Novel Porphyrin-Cryptolepine Conjugate |
| Authors: | Kumar, Anil Kumar, Dalip |
| Keywords: | Chemistry Porphyrin Cryptolepine 1,2,3-Triazole |
| Issue Date: | 2012 |
| Publisher: | CBI |
| Abstract: | A novel porphyrin–cryptolepine conjugate 7 with a 1,2,3-triazole linker was synthesized by the cycloaddition reaction of propargyl porphyrin 2 and azido cryptolepine 6 under click conditions. The conjugate 7 exhibited enhanced photocytotoxicity against A549 cells with IC50 values of 2.5 μM and 7.9 μM in the visible and UV light, respectively. |
| URI: | https://cbijournal.com/march-april-2012.php# http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/2918 |
| Appears in Collections: | Department of Chemistry |
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