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http://dspace.bits-pilani.ac.in:8080/jspui/xmlui/handle/123456789/2919| Title: | A Novel and Efficient One Pot Synthesis of 2,4-Disubstituted Thiazoles and Oxazoles Using Phenyltrimethylammoniumtribromide in Ionic Liquid |
| Authors: | Kumar, Anil |
| Keywords: | Chemistry Thiazoles Oxazoles Phenyltrimethylammoniumtribromide |
| Issue Date: | 10-Sep-2012 |
| Publisher: | Wiley |
| Abstract: | A novel and efficient one-pot procedure has been described for synthesis of 2,4-disubstituted thiazoles and oxazoles from substituted ketones using phenyltrimethylammoniumtribromide as in situ brominating agent followed by reaction with thioamide/thiourea and amides/ureas, respectively in [bmim][BF4] ionicliquid. The advantages of the procedure include avoiding the handling of lacrymetric compounds, hazardous and toxic organic solvents along with good to excellent yield of the products. |
| URI: | https://onlinelibrary.wiley.com/doi/abs/10.1002/jhet.904?jhet904-eo-0005= http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/2919 |
| Appears in Collections: | Department of Chemistry |
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