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Please use this identifier to cite or link to this item: http://dspace.bits-pilani.ac.in:8080/jspui/xmlui/handle/123456789/2977
Title: Copper catalyzed tandem oxidative C–H amination/cyclizations: Direct access to imidazo[1,2-a]pyridines
Authors: Khungar, Bharti
Kumar, Anil
Keywords: Chemistry
Copper-Catalyzed
C–H amination/cyclizations
Imidazo[1,2-a]pyridines
Issue Date: 2013
Publisher: RSC
Abstract: A simple and convenient strategy is described for the synthesis of imidazo[1,2-a]pyridines via inexpensive copper-catalyzed tandem imine formation and intramolecular aerobic oxidative C–H bond amination/cyclizations. An array of imidazo[1,2-a]pyridines were prepared by the reaction of readily available acetophenones and 2-aminopyridines in good to excellent yields (48–92%). The scope of the method was validated by a single step synthesis of Zolimidine, a drug used for peptic ulcers, in 61% yield.
URI: https://pubs.rsc.org/en/content/articlelanding/2013/RA/C3RA43889A
http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/2977
Appears in Collections:Department of Chemistry

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