2-Iodoxybenzoic Acid (IBX): A Versatile Reagent

Abstract

The importance of hypervalent iodine reagents in organic chemistry has been demonstrated in recent years, and they have been found to have several desirable properties: they are mild, selective, efficient and eco-friendly. [1] 2-Iodoxybenzoic acid (IBX) has been developed as a powerful ­reagent for several organic transformations, and a recent surge in interest was driven by the publication of an improved method for its synthesis. [2a] IBX is a powerful ­single-electron transfer oxidant that readily accepts a new heteroatom-based ligand, and has been applied successfully for the construction of novel heterocycles.