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Title: | A Facile Synthesis of Novel Bis-(indolyl)-1,3,4-oxadiazoles as Potent Cytotoxic Agents |
Authors: | Kumar, Dalip |
Keywords: | Chemistry Synthesis Novel Bis-(indolyl)-1,3,4-oxadiazoles Potent Cytotoxic Agents |
Issue Date: | 20-Sep-2012 |
Publisher: | Wiley |
Abstract: | A novel series of bis(indolyl)-1,3,4-oxadiazoles was prepared from the corresponding hydrazide-hydrazones via iodobenzene diacetate-promoted oxidative cyclization. Evaluation against a panel of human cancer cell lines revealed that some derivatives possess potent cytotoxicity with tunable selectivity for different cancer types. |
URI: | https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/cmdc.201200363 http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/3046 |
Appears in Collections: | Department of Chemistry |
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