Please use this identifier to cite or link to this item:
http://dspace.bits-pilani.ac.in:8080/jspui/xmlui/handle/123456789/3060| Title: | Synthesis and biological evaluation of indolyl chalcones as antitumor agents |
| Authors: | Kumar, Dalip |
| Keywords: | Chemistry Indolyl chalcones Anticancer agents 1,3-Diaryl-2-propen-1-ones |
| Issue Date: | Jul-2010 |
| Publisher: | Elsiever |
| Abstract: | A series of indolyl chalcones were synthesized and evaluated in vitro for their anticancer activity against three human cancer cell lines. Compounds 3b–d, 3h, 3j, 3l, 3m, 4g, and 4j showed significant cytotoxicity, particularly, indolyl chalcones 3l and 3m were identified as the most potent and selective anticancer agents with IC50 values 0.03 and 0.09 μM, against PaCa-2 cell line, respectively. |
| URI: | https://www.sciencedirect.com/science/article/pii/S0960894X10006578?via%3Dihub http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/3060 |
| Appears in Collections: | Department of Chemistry |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.