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Please use this identifier to cite or link to this item: http://dspace.bits-pilani.ac.in:8080/jspui/xmlui/handle/123456789/3060
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dc.contributor.authorKumar, Dalip-
dc.date.accessioned2021-10-27T04:21:17Z-
dc.date.available2021-10-27T04:21:17Z-
dc.date.issued2010-07-
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S0960894X10006578?via%3Dihub-
dc.identifier.urihttp://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/3060-
dc.description.abstractA series of indolyl chalcones were synthesized and evaluated in vitro for their anticancer activity against three human cancer cell lines. Compounds 3b–d, 3h, 3j, 3l, 3m, 4g, and 4j showed significant cytotoxicity, particularly, indolyl chalcones 3l and 3m were identified as the most potent and selective anticancer agents with IC50 values 0.03 and 0.09 μM, against PaCa-2 cell line, respectively.en_US
dc.language.isoenen_US
dc.publisherElsieveren_US
dc.subjectChemistryen_US
dc.subjectIndolyl chalconesen_US
dc.subjectAnticancer agentsen_US
dc.subject1,3-Diaryl-2-propen-1-onesen_US
dc.titleSynthesis and biological evaluation of indolyl chalcones as antitumor agentsen_US
dc.typeArticleen_US
Appears in Collections:Department of Chemistry

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